How does the BCL11A gene relate to hemoglobin expression?

Answers

Answer 1

The BCL11A gene is related to hemoglobin expression because it regulates the expression of the fetal hemoglobin (HbF) gene.

What is the BCL11A gene?

The BCL11A gene is a transcription factor that plays a role in the development of blood cells, and it has been shown to regulate the expression of the HbF gene.

The BCL11A gene is located on chromosome 2 in humans, and it encodes a transcription factor that plays a role in the development of blood cells. It has been found to be involved in the regulation of the expression of the fetal hemoglobin (HbF) gene.

Hemoglobin expression: Hemoglobin is a protein found in red blood cells that is responsible for carrying oxygen from the lungs to the rest of the body. Hemoglobin expression is regulated by several factors, including the BCL11A gene. The BCL11A gene has been shown to play a role in the regulation of the expression of the fetal hemoglobin (HbF) gene, which is important for the development of red blood cells in the fetus.

The BCL11A gene is an important regulator of the expression of the HbF gene, which is critical for the development of red blood cells in the fetus. Understanding the relationship between these two genes can help researchers better understand the mechanisms behind hemoglobin expression and could lead to new treatments for blood disorders like sickle cell anemia.

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Related Questions

studocu you are observing a population of lizards when you notice that the number of adults has increased and is higher than previously observed. one explanation for such an observation would include a) reduction in death rate. b) increased immigration. c) increased emigration. d) decreased emigration. e) increased birth rate.

Answers

One possible explanation for the observed increase in the number of adult lizards could be an increased birth rate. Therefore, option e) "increased birth rate" would be a potential explanation for the higher number of adults.

An increased birth rate means that more lizards are being born into the population, which contributes to an increase in the overall number of adults. This could occur due to favorable environmental conditions, availability of resources, or other factors that support successful reproduction and survival of offspring.

While options such as a) reduction in death rate, b) increased immigration, and d) decreased emigration can also contribute to an increase in the population size, they do not specifically account for the observed increase in the number of adults. Option c) increased emigration, on the other hand, suggests a decrease in the population size and would not explain the observed increase in the number of adults.

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I'm asking this out of personal curiosity, not for school. but it's still for educational purposes kinda, so I hope it's okay.

If a flower is wilted, but not totally dead and withered yet, is the flower dead and it's dead flower body is in the process of decomposing, or is the flower like in the flower stage of being an old person, it lived and now it's old, but not dead yet?

Here's an example of the flower stage I mean. ^-^

I'm asking this out of personal curiosity, not for school. but it's still for educational purposes kinda,

Answers

I think it wouldn’t be dead until it looses all of its color and is able to crumple in your fingertips. So basically, it isn’t dead yet when it is wilted. But Its getting to the stage of being dead (like how old people are at that stage of their life where they will pass away soon).

To put it simply, the flower is not dead yet, it’s just “old” :D

PLEASE HELP ASAP!!! I WILL GIVE YOU BRAINLIEST IF YOU ANSWER CORRECTLY PLEASEE!!
what happens when RNA is edited?

Answers

Answer: One type, insertion/deletion RNA editing, involves the insertion or deletion of nucleotides and actually changes the length of the target RNA. The second type, RNA editing by base modification, changes an encoded nucleotide into a different nucleotide, without changing the overall length of the RNA.

Explanation:

Answer:

Deamination produces an adenosine-to-inosine substitution, one of the most common substitutions in RNA editing.

The process of substances using a protein channel to help move from areas of high concentration to areas of low concentration without using cell energy is called: *
1. Diffusion
2. Active Transport
3. Facilitated duffusion
4. Osmosis

Answers

if I’m not wrong this process is called facilitated diffusion

during the orgasmic phase, the scrotum pulls up close to the body in preparation for ejaculation, what muscle is largely responsible for this?

Answers

The muscle responsible for this is called the cremaster muscle. This muscle is located in the scrotum and its main function is to control the temperature of the testicles by raising and lowering them in response to changes in temperature. During the orgasmic phase, the cremaster muscle contracts to pull the scrotum up close to the body, helping to prepare for ejaculation.

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Imagine something was genetically wrong with
your child, but during pregnancy you could alter
their DNA. Write a short paragraph that explains
the reasons you would give a doctor to alter the
DNA of your child.

Answers

I would like to give my child the best start in life, and altering their DNA is the best way to do that. With a few genetic tweaks, I believe my child will be more resilient to disease and illnesses, better equipped to learn new skills, and capable of increased intelligence and physical capabilities. Additionally, it will give them more protection against certain environmental influences like air and water pollution. With such a robust foundation, my child can lead a more fulfilling life, reach greater success, and be healthier overall.

which of the following is essential for the development of discrete, isolated colonies?

Answers

Solid medium is essential for development of discrete, isolated colonies Option D

What is the colony?

The growth of distinct, separate colonies requires solid media. The movement of bacteria or other microbes is restricted when a solid media, such as agar, is utilized.

Instead, they develop in confined spaces, generating distinct, isolated colonies that are visible. This makes it possible to distinguish between various kinds of microbes depending on the features of their colonies, such as their size, shape, color, or texture.

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Missing parts;

5. Which of the following is essential for development of discrete, isolated colonies?A.broth mediumB.differential mediumC.selective mediumD.solid mediumE.assay medium

a mutation that knocks out the gtpase activity of a g protein would have what effect on a cell? a) the concentration of available gtp would decrease. b) the number of g proteins in the cell would increase. c) the g protein would be inactivated by a g protein-coupled receptor/signal molecule complex. d) the g protein would always be active.

Answers

A mutation that knocks out the GTPase activity of a g protein would Option d) the G protein would always be active.

G proteins are molecular switches that cycle between an inactive GDP-bound state and an active GTP-bound state. The GTPase activity of G proteins is responsible for hydrolyzing GTP to GDP, which allows the G protein to switch back to its inactive state. This cycle of activation and inactivation is important for regulating cellular signaling pathways.

A mutation that knocks out the GTPase activity of a G protein would prevent the hydrolysis of GTP to GDP, leading to the G protein being locked in its active state. This means that the G protein would always be active, regardless of the presence or absence of signals from receptors or signal molecules. This constant activation of the G protein could disrupt normal cellular signaling processes and lead to dysregulation of downstream signaling pathways.

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You, suddenly grown very small because you drank too much TinyMe, are standing between
two cells in the trunk of the oak tree behind your apartment. Your feet are stuck in
After you free your feet, what is the first barrier that you must cross to enter any of the
surrounding cells?

You, suddenly grown very small because you drank too much TinyMe, are standing betweentwo cells in the

Answers

Answer:

I would say it's pectin secondary cell, but don't trust my word

3. Please rank the following topics from most to least interesting: (Fire Ecology - (FE), Noise Pollution and Mitigation Strategies (NP), College Majors and Careers in the Environment (CC), Great Pacific Garbage Patch (GP), EcoTourism

1.
2.
3.
4.
5.
6. ​

Answers

1.FE
2.NP
3.CC
4.EcoTourism
5.GP

abo blood type is a trait that demonstrates which type of inheritance?

Answers

that ABO blood type demonstrates multiple allele inheritance of what multiple allele inheritance means. In humans, the ABO blood type is determined by three alleles - A, B, and O. Each person one from each parent, and the are combination  these two alleles determines their blood type.

The A and B alleles are co-dominant, meaning they both express their phenotype when present together. The O allele is recessive and only expresses its phenotype when paired with another O allele. This results in four possible blood types - A, B, AB, and O. So, the inheritance of ABO blood type involves multiple alleles interacting in a complex way to determine a person's phenotype.


The ABO blood type is a trait that demonstrates the type of inheritance known as "codominance." the term are we the "codominance" refers to the type of inheritance exhibited by the ABO blood type  codominance, both alleles for are specific trait are expressed equally in an individual's phenotype, and neither allele is masked or dominates the other. The explanation for this is that ABO blood types have three alleles (A, B, and O), with both the A and B alleles being dominant over the O allele, and the A and B alleles are codominant with each other, leading to four possible blood types: A, B, AB, and O.

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Helppppppppp!!!!!!! I don’t know any of this!

Helppppppppp!!!!!!! I dont know any of this!

Answers

The answer is Polysaccharide, hope this helped :)

Which of the following genotypes would you not expect to find among
the offspring of a DdFf x ddff cross?

Ddff
DDff
DdFf
ddff

Which of the following genotypes would you not expect to find amongthe offspring of a DdFf x ddff cross?DdffDDffDdFfddff

Answers

Answer:

DDff

Explanation:

having a break with reality, usually with a person having delusional, fantastical, or hallucinatory experiences, is called ______________________________
a.psychosis b.comorbidity e.bipolarity d.multiple personality disorder e.none of these

Answers

Having a break from reality, usually with a person having delusional, fantastical, or hallucinatory experiences, is called psychosis. Therefore, option (a) is the correct answer.

Psychosis is a mental health condition characterized by a break from reality, leading to a loss of contact with external reality. A person with psychosis may experience delusions, hallucinations, disordered thinking, and abnormal behavior. Psychosis can be caused by a variety of factors, including genetics, environmental factors, substance abuse, and physical or mental illness. It is often associated with conditions such as schizophrenia, bipolar disorder, and severe depression, but can also occur in other mental health conditions or as a result of drug use.

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Why is bacteria and archaea not in the same kingdom

Answers

Archaea doesn’t have a membrane bound nucleus and also lacks internal cell organelles
They have different structures such as the lack of membrane bound organelles and what is used to make the cell wall

photoreceptors that are specialized for daylight vision, fine acuity, and color are called

Answers

Answer:

Cone cells

Explanation:

Cone cells, or cones, are photoreceptor cells in the retinas of vertebrates' eyes, including the human eye. They respond differently to light of different wavelengths, and the combination of their responses is responsible for color vision.

Caitlyn, juan, and elena are partners in fruit orchard farms. caitlyn gives notice to quit the firm, which otherwise continues to do business. this is:_________

Answers

Caitlyn's notice to leave the partnership is a withdrawal, which can result in the partnership being dissolved; however, if the other partners continue the business, it will be recreated without the withdrawing partner.

The situation described is the removal of a partner from a partnership, which results in the partnership's dissolution if the surviving partners decide not to continue the operation. If the surviving partners elect to keep the company going, the partnership will be reconstructed without the departing partner. This is referred to as a partnership dissolution.

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Plant cells have some organelles that animal cells do not. Check all organelles that ONLY plant cells have.

A
chloroplast
B
nucleus
C
cell membrane
D
cytoplasm
E
cell wall
F
mitochondria

Answers

Answer: Plant cells only have chloroplast and a cell wall. Which is A and E.

what statement correctly compares a law and a theory?

Answers

Answer:

A law is a fact that cannot be changed, A theory however can be changed over the course of time.

Explanation:

I took tests

Whose ability to use fossils in stratigraphy was identified as a major breakthrough in
sequencing rock layers?
Carl Gilbert and Willard Libby
Georges Cuvier and William Smith
James Hutton and Nicholas Steno
Stephen Calvert and Charles Lyell

Answers

William Smith and Georges Cuvier

TRUE/FALSE. Corynebacterium diphtheriae is very invasive and can cause direct damage to the heart, kidneys and nerves.

Answers

TRUE. Corynebacterium diphtheriae is a bacterium that can cause diphtheria, a serious and potentially fatal disease.

The bacteria produce a toxin that can damage tissues in the body, including the heart, kidneys, and nerves. In severe cases, diphtheria can cause heart failure, paralysis, and even death.

The bacteria are highly contagious and can be spread through respiratory droplets or contact with infected skin or objects. Vaccination is the best way to prevent diphtheria, and early treatment with antibiotics and antitoxin is critical for those who are infected. It is important to seek medical attention if you have symptoms of diphtheria or have been exposed to someone who has the disease.

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3.
How can changes to the structure of DNA lead to the development of new traits in a species?

Answers

Answer:

An organism's DNA affects how it looks, how it behaves, and its physiology.

So a change in an organism's DNA can cause changes in all aspects of its life. Mutations are essential to evolution; they are the raw material of genetic variation.

Explanation:

Answer:

A mutation is a change in DNA the heriditary material of life the organisms DNA affects how it looks ,how it behaves and it's physiology so therefore the change in an organisms DNA can causes changes in all aspects of its life the mutations are very essential to evolution they are the raw material of genetic variation.

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It might help u

vinclozolin is a fungicide that is used on grapes, fruits, and vegetables. it also acts as an androgen receptor antagonist, which prevents testosterone from binding to the receptor. vinclozolin has also been shown to have epigenetic effects. why is vinclozolin exposure a potentially larger issue than other environmental chemical exposures that do not cause epigenetic changes?

Answers

Vinclozolin exposure is a potentially larger issue than other environmental chemical exposures that do not cause epigenetic changes because, as an androgen receptor antagonist, it can disrupt the normal functioning of hormones like testosterone.

Vinclozolin is a fungicide that is used on various crops such as grapes, fruits, and vegetables. While it is effective in controlling fungal diseases, it also has an unintended effect on the human body. Vinclozolin acts as an androgen receptor antagonist, which means that it prevents testosterone from binding to the receptor. This can lead to a variety of negative health effects, including developmental abnormalities, reproductive problems, and even cancer.

What makes vinclozolin exposure potentially more concerning than other environmental chemical exposures is its ability to cause epigenetic changes. Epigenetics refers to changes in gene expression that occur without any alteration to the DNA sequence. These changes can be passed down through generations and can have significant impacts on health outcomes.


Studies have shown that vinclozolin exposure can cause epigenetic changes in animals, specifically in their sperm cells. These changes can lead to decreased fertility, abnormal development of reproductive organs, and even increased susceptibility to disease.

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In the following images, identify the solution tonicity. Is it (isotonic, hypertonic, hypotonic) and give an explanation as to how you know?Tonicity of right side: How you know:Tonicity of A in plant cell:How you know:Tonicity of B in plant cell:How you know:

In the following images, identify the solution tonicity. Is it (isotonic, hypertonic, hypotonic) and
In the following images, identify the solution tonicity. Is it (isotonic, hypertonic, hypotonic) and

Answers

The tonicity of the image (B) on the right side shows hypertonic tonicity. If plant cells are situated in a hypertonic solution where it contains a higher solute concentration, water will shift from inside to the outside of the cell with subsequent shrinking of the cell or plasmolyzed. This is happening in osmosis.

The tonicity of the image (A) on the left side shows hypotonic tonicity. Tonicity is used by plants to give them a boost in their structural support to maintain its cells in a bloated state (inflated with water). There is a segregation of dissolved solutes in a central vacuole that will cause the solution hypotonic.

How does the size of the soil particles impact
the soil's permeability (movement of water)?

Answers

Answer:

Water moves by gravity into the open pore spaces in the soil, and the size of the soil particles and their spacing determines how much water can flow in. Wide pore spacing at the soil surface increases the rate of water infiltration, so coarse soils have a higher infiltration rate than fine soils.

How does soil particle size affect permeability?

But permeability is a different thing. It increases as particle size increases. By definition, permeability is a MEASURE OF EASE with which fluids will flow though a porous rock, soil or sediment. ... That means capillarity increase as particle sizes decreases.

What do you think is the importance of these cellular processes in living things? 1. Photosynthesis 2. Cellular Respiration

Answers

1. help maintain the balance of carbon and oxygen in the air

2 Respiration provide cells with oxgen

Please help I will give brainliest

Please help I will give brainliest

Answers

Answer:

its correct option is A)Nucleus

Explanation:

in a salt solution ,salt is to,___while water is ____
A.solute,solvent
B.solvent,solute
C.seasoning,water
D.solubility,concentration

Answers

Answer:

Solute , Solvent

Solute Is the substance which is less in amount and which is mix in a solution

Solvent is the substances which is more in amount and in which the solute is mixed.

The first option is correct:)

a polysaccharide- nucleus of an atom- a carbon atom- proton- a molecule of glucosewrite the smallest to the largest

Answers

The smallest to the largest are the proton, nucleus of an atom, carbon atom, molecule of glucose, and polysaccharide. Here, the proton is present inside an atom, which is the smallest of all.

Protons are subatomic particles that is positive in nature and carry a positive charge, and the nucleus of an atom has a bigger size. Polysaccharides are complex carbohydrates that is made up of many simple units of sugar units bonded together by glycosidic bonds. They are generally larger molecules than individual glucose molecules and insoluble in water. Examples of polysaccharides include starch, cellulose, and glycogen and many more.

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when an hfr e. coli cell engages in conjugation with an f- cell, what will be transferred to the recipient cell if the conjugation bridge is broken after 20 minutes?

Answers

When an Hfr E. coli cell engages in conjugation with f- cell, then part of the F plasmid and portion of the bacterial chromosome is transferred to the recipient cell if the conjugation bridge is broken after 20 minutes.

What do you know about Hfr E.coli?

High-frequency recombination(Hfr) cell is a bacterium with a conjugative plasmid integrated into its chromosomal DNA and the integration of plasmid in the cell's chromosome is through homologous recombination.

After the cross between Hfr cell and F- cell, recipient cell remains recipient and in this conjugation, chromosomal DNA is transferred from donor to recipient cell with the portion of F- factor. Therefore, the frequency of recombination is high.

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Other Questions
A tank is full of water when a valve at the bottom of the tank is opened. The equation V = 62(151 - t) gives the volume of water in the tank, in cubic meters, after t hours.What is the volume of water in the tank before the valve is opened?__ cubic metersHow long does it take the tank to fully empty?___ hoursFind an equation for DV/dtdV/dt = __ PreviewWhat is the flow rate after 23 hours? ____ Select an answerWhen is the water flowing out of the tank the fastest?t= ____ hours Sports Inc. has developed a shoe to compete with Air Jordans. In order to keep up with competitors and minimize competitor market power, the firm decides to sell branded sports equipment as well. By introducing another new business so soon outside of its shoe products, the firm stands to lose value. Sports Inc.'s reason for diversifying itself is to:a. neutralize another firm's advantage by acquiring a similar distribution outlet.b. decrease another firm's advantage by acquiring a similar distribution outlet.c. increase its value by acquiring a similar distribution outlet as a competitor.d. decrease another firm's value by acquiring a different distribution outlet.What is the distinction between value-neutral reasons and value-increase reasons for a firm to diversify?a. Value-neutral reasons seek to help the firm develop a more competitive position, whereas value-increase reasons seek to serve the managers of the firm.b. Value-neutral reasons seek to serve the managers of the firm, whereas value-increase reasons seek to establish a more competitive position.c. Value-neutral reasons seek to improve the firm overall, whereas value-increase reasons seek to establish a more competitive position.d. Value-neutral reasons seek to help the firm develop a better competitive position, whereas value-increase reasons seek to improve the firm overall. Using proper arrow formalism, write down a mechanism for the reaction between methyl pyruvate and benzylamine in order to produce a corresponding Schiff base. If acid is required in your mechanism, use HA as a generic acid.a. How would you expect the IR spectrum of methyl pyruvate to differ from the Schiff base product formed in Part 1?Be specific with the location of the different, distinct IR signals that would be present in each compound, and which functional groups they correspond to Use the Random Number generator to write a java application that simulates a pair of dice.- Throwing the pair of dice 10,000 times- Add the values for the pair- Print the frequency at the end of 10,000 runs When managers start talking about improving productivity, employees usually react _____.a. in a positive wayb. with fear of unknown changesc. with a desire for changes Complete the function CountCharacters0 that takes one string parameter and one character parameter. The function returns the number of characters in the string that are not equal to the character parameter. Ex if the input is bkvt g, then the outpot is: } int main (){string instring; char x; int result; cin inString;cin xresult = CountCharacters (inString, x)cout result endl;return ;} Looking at the Low Tech Market Segment's "Market Share Actual vs. Potential" chart, what is a priority for company Andrews in the next round for product Able to maximize sales volumes? (Refer to the Round 2 Foundation FastTrack Report available both on Blackboard and in Appendix 1 of "An Introduction to Business.") Peters, a suburban homeowner, decided to resurface with bricks the concrete area surrounding his pool. He purchased from Homeco, a local homeimprovement store, a concrete cutter manufactured by Conco, which had a blade manufactured by Bladeco. He then took the concrete cutter home and assembled it following the instructions provided by Conco.The blade that Peters purchased was clearly labeled "Wet." Although noinstructions or warnings came with the blade, Conco included several warnings throughout the instructions to the concrete cutter stating, "If using a wet blade, frequently water the blade and surface being cut to avoid risk of blade degradation." No other warnings relating to the blade were included with theconcrete cutter.Peters began cutting the concrete with the concrete cutter without using water.Less than five minutes into the job he noticed that the cutter was vibrating excessively. He turned the machine off by hitting the "kill switch" located near the blade at the bottom of the cutter, with his right foot. The cutter's handle did not have a "kill switch." After carefully examining the concrete cutter and blade,Peters became convinced that nothing was wrong and continued to operate it.Nevertheless, within seconds, the concrete cutter again began vibrating violently.As Peters reached with his right foot to hit the "kill switch" again, the blade broke into pieces, forced off the cutter's safety guard, spiraled into Peter's right foot and caused permanent injuries.On what theory or theories might Peters recover damages from and whatdefenses may reasonably be raised by:1. Conco? Discuss. d. explain in a nontechnical way why demand is elastic in the upper-left segment of the demand curve and inelastic in the lower-right segment. instructions: in order to receive full credit, you must make a selection for each option. for correct answer(s), click the box once to place a check mark. for incorrect answer(s), click the option twice to empty the box.O When the initial price is high and the initial quantity is low, the percentage change in quantity exceeds the percentage change in price,making demand elasticO When the initial price is low and the initial quantity is high, the percentage change in quantity is less than the percentage change in price,making demand elastic.O When the initial price is low and the initial quantity is high, the percentage change in quantity is less than the percentage change in price,making demand inelastic.O When the initial price is high and the initial quantity is low, the percentage change in quantity exceeds the percentage change in price,making demand inelastic Which of the following is a term used to describe excessive nitrogenous waster in the blood, as seen in acute glomerulonephritis?a) Azotemiab) Proteinuriac) Hematuriad) Bacteremia True or False - Temperatures in the desert did not fluctuate (change) much from day to night Surveys in several Western countries suggest that between _____ percent of women develop a full case of bulimia nervosa. To stretch a spring 5.00cm from its unstretched length, 19.0J of work must be done.1- what is the force constant of the spring ?2- What magnitude force is needed to stretch the spring 5.00cm from its unstretched length?3- How much work must be done to compress this spring 4.00 cm from its unstretched length?4-What force is needed to stretch it this distance? Juan believes that the prefrontal cortex is responsible for consciousness. Pierre disagrees,saying that no single area of the brain is responsible for consciousness, and that insteadspecific areas process certain types of information. Pierre most likely believes in the__________ model of consciousness.a. dissociationb.activation synthesisc.restorative HHHHEEEEELLLPPPPPPSolve for x. using the tangent lines.50 degXx =[?]^ which statement best explains how max weber compares hindus to protestants?multiple choice question.hindus focus on the pursuit of material goods.hindus would be less likely to engage in entrepreneurial activity.protestants would be less likely to engage in entrepreneurial activity.protestants focus on an ascetic lifestyle. Considering the fact that many of the health problems of older adults are chronic rather than acute, which of the following is a concern regarding the medical system?Medicare does not have special provisions for chronic illnesses.Costs of prescription drugs are still not subsidized for the elderly.The medical system is still based on a "cure" rather than a "care" model.Home-visits are not emphasized over hospital stays. Bob and April own a house at the beach. The house was rented to unrelated parties for 8 weeksduring the year. April and the children used the house 12 days for their vacation during the year.After properly dividing the expenses between rental and personal use, it was determined that a losswas incurred as follows:Gross rental income $4,000Less: Mortgage interest and property taxes $3,500Other allocated expenses 2,000 (5,500)Net rental loss ($1,500)What is the correct treatment of the rental income and expenses on Bob and April's joint income taxreturn for the current year assuming the IRS approach is used if applicable?A. A $1,500 loss should be reported.B. Only the mortgage interest and property taxes should be deducted.C. Since the house was used more than 10 days personally by Bob and April, the rental expenses(other than mortgage interest and property taxes) are limited to the gross rental income in excessof deductions for interest and taxes allocated to the rental use.D. Since the house was used less than 50% personally by Bob and April, all expenses allocated topersonal use may be deducted.E. Bob and April should include none of the income or expenses related to the beach house in theircurrent year income tax return. For financial statement audits, generally accepted government auditing standards (GAGS) incorporate the Statements on Auditing Standards (SAS) that are issued by the AICPA. GAGAS prescribe additional standards on:1. direct reporting of illegal acts2. reporting on internal controls exercise 4.32 write a method called sum with a while loop that adds up all numbers between two numbers a and b. the values for a and b can be passed to the sum method as parameters.